From Isolated Vessels
نویسنده
چکیده
In 1980, Furchgott and Zawadskil first showed that an intact endothelium must be present for acetylcholine to relax isolated vessels. This was subsequently found to be true for many other vasoactive substances.2-6 As a result of work from several laboratories, this response has been shown to occur because the endothelium releases a shortlived nonprostanoid compound or family of compounds collectively termed the "endothelium-
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Altered endothelial function in isolated human myometrial vessels induced by plasma from women with pre-eclampsia is not reproducible in isolated mouse vessels.
In order to facilitate characterization of the circulating factor(s) in pre-eclampsia, the present study aimed to determine whether plasma from women with pre-eclampsia, which induces attenuated endothelial-dependent relaxation in human myometrial arteries, is also capable of inducing altered endothelial function in mouse vessels. Human vessels were isolated from myometrial biopsies taken from ...
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